EPHB2

Gene

EPH receptor B2

HGNCHGNC:3393 EnsemblENSG00000133216 NCBI Gene2048

Locus: gene with protein productLocation: 1p36.12

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDRT · ERK · EPHT3 · Hek5 · Tyro5

View full nomenclature history (6)

Previous symbolsDRT, ERK, EPHT3

Alias symbolsHek5, Tyro5

Previous namesEphB2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Familial prostate cancer

Rare hemorrhagic disorder due to a constitutional platelet anomaly

Neoplasms

Osteoarthritis, Hip

Carcinoma, Non-Small-Cell Lung

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Sterile alpha motif domain containingEPH receptorsMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.