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ERG

Gene

ETS transcription factor ERG

HGNCHGNC:3446EnsemblENSG00000157554NCBI Gene2078
Locus: gene with protein productLocation: 21q22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known aserg-3 · p55
View full nomenclature history (8)
Alias symbolserg-3, p55
Previous namesv-ets avian erythroblastosis virus E26 oncogene related, v-ets avian erythroblastosis virus E26 oncogene homolog
Alias namestranscriptional regulator ERG (transforming protein ERG), v-ets erythroblastosis virus E26 oncogene like, TMPRSS2-ERG prostate cancer specific, ETS-related gene

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

B-cell acute lymphoblastic leukemia
Multiple Sclerosis
Osteoarthritis, Hip
Neurodegenerative Diseases
Prostate carcinoma
Dupuytren Contracture

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

ETS transcription factor family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.