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FKBP5

Gene

FKBP prolyl isomerase 5

HGNCHGNC:3721EnsemblENSG00000096060NCBI Gene2289
Locus: gene with protein productLocation: 6p21.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFKBP51 · FKBP54 · PPIase · P54 · Ptg-10
View full nomenclature history (7)
Alias symbolsFKBP51, FKBP54, PPIase, P54, Ptg-10
Previous namesFK506-binding protein 5, FK506 binding protein 5

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hypothyroidism
Thyroid Diseases
Colitis, Ulcerative
Ovarian dysfunction
Osteoarthritis, Hip
Asthma
Parasitic Diseases
Arthritis, Rheumatoid
Dermatitis, Contact

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Tetratricopeptide repeat domain containingFKBP prolyl isomerase familyMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.