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GOT2

Gene

glutamic-oxaloacetic transaminase 2

HGNCHGNC:4433EnsemblENSG00000125166NCBI Gene2806
Locus: gene with protein productLocation: 16q21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asmitAAT · KATIV · KAT4 · KYAT4 · mAspAT
View full nomenclature history (10)
Alias symbolsmitAAT, KATIV, KAT4, KYAT4, mAspAT
Previous namesglutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2), glutamic-oxaloacetic transaminase 2, mitochondrial
Alias nameskynurenine aminotransferase IV, aspartate aminotransferase 2, aspartate transaminase 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic developmental and epileptic encephalopathy
Neurodegenerative Diseases
Alcohol drinking
Malignant epithelial tumor of ovary
Anaphylaxis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Glutamic-oxaloacetic transaminase family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-07-24.
Open TargetsGene–disease associations from the Open Targets Platform.