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GRHL3

Gene

grainyhead like transcription factor 3

HGNCHGNC:25839EnsemblENSG00000158055NCBI Gene57822
Locus: gene with protein productLocation: 1p36.11

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTFCP2L4 · SOM
View full nomenclature history (5)
Previous symbolsTFCP2L4
Alias symbolsSOM
Previous namestranscription factor CP2-like 4, grainyhead-like 3 (Drosophila)
Alias namessister-of-mammalian grainyhead

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cleft Palate
Genetic Diseases, Inborn
Cleft Lip
Cardiomyopathy, Hypertrophic

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Grainyhead like transcription factor family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.