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GTF2H3

Gene

general transcription factor IIH subunit 3

HGNCHGNC:4657EnsemblENSG00000111358NCBI Gene2967
Locus: gene with protein productLocation: 12q24.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asBTF2 · TFIIH · P34
View full nomenclature history (5)
Alias symbolsBTF2, TFIIH, P34
Previous namesgeneral transcription factor IIH, polypeptide 3 (34kD subunit), general transcription factor IIH, polypeptide 3, 34kDa

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

HIV Infections
Alcohol drinking
Neurodegenerative Diseases
Leukoencephalopathies
Brugada syndrome
Familial progressive cardiac conduction defect
Atrial Fibrillation

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Nucleotide excision repairGeneral transcription factor IIH complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.