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Disease

Brugada syndrome

Late-stage therapeutic development
Also known as Bangungut, Brugada type idiopathic ventricular fibrillation, Pokkuri death syndrome, SUNDS+5 more

Bangungut, Brugada type idiopathic ventricular fibrillation, Pokkuri death syndrome, SUNDS, dream disease, idiopathic ventricular fibrillation, Brugada type, right bundle branch block, ST segment elevation, and sudden death syndrome, sudden unexplained nocturnal death syndrome, sudden unexpected nocturnal death syndrome.

6
Clinical trials
12
Associated genes
5
Related proteins
Current focus
Beta-arrestin-1 biologySemaphorin-3a biologyTherapeutic development

What's happening now

An analyst briefing on current research, clinical, regulatory and industry activity surrounding this disease.

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Clinical trials

6 sponsors · 0 new · 0 completed in the last 12 months (net +0)

The current development programme across all trial phases.

Associated genes

12 matches

Genes associated with this disease in the canonical knowledge graph (Open Targets evidence). Number shows the association score.

Disease biology

5 matches

Proteins whose encoding gene is associated with this disease, reached through the canonical gene→disease graph. Number shows the gene's association score.

Reference

Authoritative identity, definition & identifiers.

Defined in MeSH

An autosomal dominant defect of cardiac conduction that is characterized by an abnormal ST-segment in leads V1-V3 on the ELECTROCARDIOGRAM resembling a right BUNDLE-BRANCH BLOCK; high risk of VENTRICULAR TACHYCARDIA; or VENTRICULAR FIBRILLATION; SYNCOPAL EPISODE; and possible sudden death. This syndrome is linked to mutations of gene encoding the cardiac SODIUM CHANNEL alpha subunit.

Synonyms

Bangungut, Brugada type idiopathic ventricular fibrillation, Pokkuri death syndrome, SUNDS, dream disease, idiopathic ventricular fibrillation, Brugada type, right bundle branch block, ST segment elevation, and sudden death syndrome, sudden unexplained nocturnal death syndrome, sudden unexpected nocturnal death syndrome

References & data sources
  • Disease identity & definition — NLM Medical Subject Headings (MeSH), public domain
  • Clinical trials — ClinicalTrials.gov (U.S. National Library of Medicine)
  • Related entities are derived from literature co-mention (studied together) — associative, not causal.