Back to discover

SEMA3A

Gene

semaphorin 3A

HGNCHGNC:10723EnsemblENSG00000075213NCBI Gene10371
Locus: gene with protein productLocation: 7q21.11

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Semaphorin-3AQ14563

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSEMAD · SEMA1 · SemD · coll-1 · Hsema-I
View full nomenclature history (7)
Previous symbolsSEMAD
Alias symbolsSEMA1, SemD, coll-1, Hsema-I
Previous namessema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
Alias namessema III

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Kallmann syndrome
Alcohol drinking
Glaucoma, Open-Angle
Brugada syndrome
Heart Defects, Congenital
Glaucoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Immunoglobulin like domain containingSemaphorins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.