GTF3C5

Gene

general transcription factor IIIC subunit 5

HGNCHGNC:4668 EnsemblENSG00000148308 NCBI Gene9328

Locus: gene with protein productLocation: 9q34.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asTFiiiC2-63 · TFIIIC63 · TFIIICepsilon

View full nomenclature history (6)

Alias symbolsTFiiiC2-63, TFIIIC63, TFIIICepsilon

Previous namesgeneral transcription factor IIIC, polypeptide 5 (63kD), general transcription factor IIIC, polypeptide 5, 63kDa

Alias namestranscription factor IIIC, 63 kD

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Complex neurodevelopmental disorder

Neurodevelopmental Disorders

Hemorrhagic disease

Thrombocytopenia 4

Neuroendocrine Tumors

Myeloproliferative disorder

Myopathy, myofibrillar, 12, infantile-onset, with cardiomyopathy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genesGeneral transcription factor IIIC complex subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.