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GYPB

Gene

glycophorin B (MNS blood group)

HGNCHGNC:4703EnsemblENSG00000250361NCBI Gene2994
Locus: gene with protein productLocation: 4q31.21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMNS · GPB · SS · CD235b · PAS-3
View full nomenclature history (9)
Previous symbolsMNS
Alias symbolsGPB, SS, CD235b, PAS-3
Previous namesglycophorin B (includes Ss blood group), glycophorin B (Ss blood group)
Alias namesSs sialoglycoprotein, Sialoglycoprotein delta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Malaria
Pulmonary Disease, Chronic Obstructive
Thyroid Neoplasms
Nephrotic Syndrome
Gout
Ovarian dysfunction
Immune System Diseases
Placental abruption

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Blood group antigensCD molecules

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.