H3C3

Gene

H3 clustered histone 3

HGNCHGNC:4768 EnsemblENSG00000287080 NCBI Gene8352

Locus: gene with protein productLocation: 6p22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asH3FC · HIST1H3C · H3/c · H3.1

View full nomenclature history (8)

Previous symbolsH3FC, HIST1H3C

Alias symbolsH3/c, H3.1

Previous namesH3 histone family, member C, histone 1, H3c, histone cluster 1, H3c, histone cluster 1 H3 family member c

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Communicable Diseases

Lupus Erythematosus, Systemic

Diffuse Intrinsic Pontine Glioma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

H3 histonesProteins encoded by multiple genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-10-20.

Open TargetsGene–disease associations from the Open Targets Platform.