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HECTD4

Gene

HECT domain E3 ubiquitin protein ligase 4

HGNCHGNC:26611EnsemblENSG00000173064NCBI Gene283450
Locus: gene with protein productLocation: 12q24.13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC12orf51 · FLJ34154 · KIAA0614
View full nomenclature history (5)
Previous symbolsC12orf51
Alias symbolsFLJ34154, KIAA0614
Previous nameschromosome 12 open reading frame 51, HECT domain containing E3 ubiquitin protein ligase 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Angina Pectoris
Gout
Stroke
Ischemic Stroke
Hypertension
Graves' Disease
Myocardial Infarction
Alcohol drinking

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MicroRNA protein coding host genesHECT domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.
Open TargetsGene–disease associations from the Open Targets Platform.