Back to discover

HPSE2

Gene

heparanase 2 (inactive)

HGNCHGNC:18374EnsemblENSG00000172987NCBI Gene60495
Locus: gene with protein productLocation: 10q24.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asUFS · HPA2 · HPR2
View full nomenclature history (5)
Previous symbolsUFS
Alias symbolsHPA2, HPR2
Previous namesurofacial syndrome, heparanase 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Migraine Disorders
Ureterolithiasis
Headache Disorders
Joint Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Heparanase familyMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.