IGFBP2

Gene

insulin like growth factor binding protein 2

HGNCHGNC:5471 EnsemblENSG00000115457 NCBI Gene3485

Locus: gene with protein productLocation: 2q35

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Insulin-like growth factor-binding protein 2P18065

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asIBP2

View full nomenclature history (4)

Previous symbolsIBP2

Previous namesinsulin-like growth factor binding protein 2 (36kD), insulin-like growth factor binding protein 2, 36kDa, insulin-like growth factor binding protein 2

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Intelligence

Pregnancy Complications

Glaucoma, Open-Angle

Central Nervous System Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Insulin like growth factor binding proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.