IKZF1

Gene

IKAROS family zinc finger 1

HGNCHGNC:13176 EnsemblENSG00000185811 NCBI Gene10320

Locus: gene with protein productLocation: 7p12.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asZNFN1A1 · hIk-1 · LyF-1 · Hs.54452 · IKAROS · PPP1R92

View full nomenclature history (9)

Previous symbolsZNFN1A1

Alias symbolshIk-1, LyF-1, Hs.54452, IKAROS, PPP1R92

Previous nameszinc finger protein, subfamily 1A, 1 (Ikaros), IKAROS family zinc finger 1 (Ikaros)

Alias namesprotein phosphatase 1, regulatory subunit 92

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Precursor Cell Lymphoblastic Leukemia-Lymphoma

B-cell acute lymphoblastic leukemia

Leukemia, Myeloid, Acute

Cutaneous melanoma

Lupus Erythematosus, Systemic

Crohn's Disease

Melanoma

Lung carcinoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typeProtein phosphatase 1 regulatory subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-15.

Open TargetsGene–disease associations from the Open Targets Platform.