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IL16

Gene

interleukin 16

HGNCHGNC:5980EnsemblENSG00000172349NCBI Gene3603
Locus: gene with protein productLocation: 15q25.1

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Pro-interleukin-16Q14005

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLCF · IL-16 · prIL-16 · HsT19289 · FLJ42735 · FLJ16806
View full nomenclature history (9)
Alias symbolsLCF, IL-16, prIL-16, HsT19289, FLJ42735, FLJ16806
Previous namesinterleukin 16 (lymphocyte chemoattractant factor)
Alias namesprointerleukin 16, lymphocyte chemoattractant factor

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hair color
Primary biliary cholangitis
Urolithiasis
Alcohol drinking
Neoplasms
Sarcopenia

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

InterleukinsPDZ domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.