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IRAG1

Gene

inositol 1,4,5-triphosphate receptor associated 1

HGNCHGNC:7237EnsemblENSG00000072952NCBI Gene10335
Locus: gene with protein productLocation: 11p15.4

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMRVI1 · JAW1L · IRAG
View full nomenclature history (6)
Previous symbolsMRVI1
Alias symbolsJAW1L, IRAG
Previous namesmurine retrovirus integration site 1 homolog
Alias namesinositol 1,4,5-triphosphate-associated cGMP kinase substrate, IP3R-associated cGMP kinase substrate

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Migraine Disorders
Asthma
Migraine with Aura
Childhood onset asthma
Coronary Artery Disease
Hemorrhoid

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.