ISL2

Gene

ISL LIM homeobox 2

HGNCHGNC:18524 EnsemblENSG00000159556 NCBI Gene64843

Locus: gene with protein productLocation: 15q24.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFLJ10160

View full nomenclature history (2)

Alias symbolsFLJ10160

Previous namesISL2 transcription factor, LIM/homeodomain, (islet-2)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Meniere's Disease

Sleep Apnea Syndromes

Smoking cessation

Central Nervous System Neoplasms

Glioma

Meningitis

Sleep Apnea, Obstructive

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

LIM class homeoboxes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.