ITGAL

Gene

integrin subunit alpha L

HGNCHGNC:6148 EnsemblENSG00000005844 NCBI Gene3683

Locus: gene with protein productLocation: 16p11.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCD11A · HNA-5 · LFA-1 · LFA1A

View full nomenclature history (8)

Previous symbolsCD11A

Alias symbolsHNA-5, LFA-1, LFA1A

Previous namesintegrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

Alias nameshuman neutrophil antigen 5, antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Inflammatory Bowel Diseases

Pulmonary Disease, Chronic Obstructive

Gastroesophageal Reflux

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesIntegrin alpha subunitsMicroRNA protein coding host genesHuman neutrophil antigens

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-02-13.

Open TargetsGene–disease associations from the Open Targets Platform.