ITGAX

Gene

integrin subunit alpha X

HGNCHGNC:6152 EnsemblENSG00000140678 NCBI Gene3687

Locus: gene with protein productLocation: 16p11.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asCD11C

View full nomenclature history (4)

Alias symbolsCD11C

Previous namesintegrin, alpha X (antigen CD11C (p150), alpha polypeptide), integrin, alpha X (complement component 3 receptor 4 subunit)

Alias namescomplement component 3 receptor 4 subunit

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Glomerulonephritis, IGA

Neurodegenerative Diseases

Lupus Erythematosus, Systemic

Carcinoma, Hepatocellular

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesIntegrin alpha subunitsComplement system regulators and receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.