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KLK4

Gene

kallikrein related peptidase 4

HGNCHGNC:6365EnsemblENSG00000167749NCBI Gene9622
Locus: gene with protein productLocation: 19q13.41

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPRSS17 · PSTS · EMSP · EMSP1 · KLK-L1
View full nomenclature history (7)
Previous symbolsPRSS17
Alias symbolsPSTS, EMSP, EMSP1, KLK-L1
Previous nameskallikrein 4 (prostase, enamel matrix, prostate)
Alias namesenamel matrix serine proteinase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Amelogenesis imperfecta
Graves' Disease
Stroke
Genetic Diseases, Inborn
Alcohol drinking
Infertility, Male
Prostate carcinoma
Prostatic Neoplasms
Familial prostate cancer

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Kallikreins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.