KPNA2

Gene

karyopherin subunit alpha 2

HGNCHGNC:6395 EnsemblENSG00000182481 NCBI Gene3838

Locus: gene with protein productLocation: 17q24.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRCH1 · SRP1alpha · IPOA1 · QIP2 · PTAC58

View full nomenclature history (10)

Previous symbolsRCH1

Alias symbolsSRP1alpha, IPOA1, QIP2, PTAC58

Previous nameskaryopherin alpha 2 (RAG cohort 1, importin alpha 1), karyopherin alpha 2

Alias namesimportin alpha 1, nuclear pore-targeting complex 58kD component, RAG cohort 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Severe Acute Respiratory Syndrome

Dengue

Influenza, Human

COVID-19

Diabetes Mellitus, Type 2

Hypertension

Peripheral Arterial Disease

Non-alcoholic Fatty Liver Disease

Substance-Related Disorders

Risk-taking behaviour

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Armadillo repeat containingImportins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.