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LCLAT1

Gene

lysocardiolipin acyltransferase 1

HGNCHGNC:26756EnsemblENSG00000172954NCBI Gene253558
Locus: gene with protein productLocation: 2p23.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asLYCAT · FLJ37965 · ALCAT1 · AGPAT8 · LPLAT6
View full nomenclature history (8)
Previous symbolsLYCAT
Alias symbolsFLJ37965, ALCAT1, AGPAT8, LPLAT6
Previous nameslysocardiolipin acyltransferase
Alias namesacyl-CoA:lysocardiolipin acyltransferase 1, 1ysophospholipid acyltransferase 6

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Alopecia
Iron Metabolism Disorders
Smoking initiation
Alcohol drinking

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

1-acylglycerol-3-phosphate O-acyltransferasesLysophospholipid acyltransferases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.