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MARCHF8

Gene

membrane associated ring-CH-type finger 8

HGNCHGNC:23356EnsemblENSG00000165406NCBI Gene220972
Locus: gene with protein productLocation: 10q11.21-q11.22

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMIR · MARCH8 · c-MIR · CMIR · MARCH-VIII · RNF178
View full nomenclature history (11)
Previous symbolsMIR, MARCH8
Alias symbolsc-MIR, CMIR, MARCH-VIII, RNF178
Previous namesc-mir, cellular modulator of immune recognition, membrane-associated ring finger (C3HC4) 8, membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
Alias namesE3 ubiquitin-protein ligase MARCHF8, ring finger protein 178

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cholelithiasis
Gallstones
Alcohol drinking
Prostate carcinoma
Prostatic Neoplasms
Wounds and Injuries
Neoplasms
Carcinoma, Non-Small-Cell Lung

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Ring finger proteinsMembrane associated ring-CH-type fingers

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-10-17.
Open TargetsGene–disease associations from the Open Targets Platform.