MAVS

Gene

mitochondrial antiviral signaling protein

HGNCHGNC:29233 EnsemblENSG00000088888 NCBI Gene57506

Locus: gene with protein productLocation: 20p13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asVISA · KIAA1271 · IPS-1 · Cardif

View full nomenclature history (7)

Alias symbolsVISA, KIAA1271, IPS-1, Cardif

Alias namesvirus-induced signaling adaptor, IFN-B promoter stimulator 1, CARD adaptor inducing IFN-beta

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Severe Acute Respiratory Syndrome

Neurodegenerative Diseases

Lysosomal Storage Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Caspase recruitment domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.