MCM6

Gene

minichromosome maintenance complex component 6

HGNCHGNC:6949 EnsemblENSG00000076003 NCBI Gene4175

Locus: gene with protein productLocation: 2q21.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMis5

View full nomenclature history (5)

Alias symbolsMis5

Previous namesMCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae), minichromosome maintenance deficient (mis5, S. pombe) 6, minichromosome maintenance deficient 6 homolog (S. cerevisiae)

Alias namesMIS5 homolog (S.pombe)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Sprain

Lupus Erythematosus, Systemic

Neurodevelopmental Disorders

Obesity, Morbid

Carcinoma, Hepatocellular

Breast Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

MCM familyminichromosome maintenance 2-7 complex

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.