NCF4

Gene

neutrophil cytosolic factor 4

HGNCHGNC:7662 EnsemblENSG00000100365 NCBI Gene4689

Locus: gene with protein productLocation: 22q12.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asp40phox · SH3PXD4

View full nomenclature history (5)

Alias symbolsp40phox, SH3PXD4

Previous namesneutrophil cytosolic factor 4 (40kD), neutrophil cytosolic factor 4, 40kDa

Alias namesneutrophil NADPH oxidase factor 4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Granulomatous Disease, Chronic

Inflammatory Bowel Diseases

Respiratory Tract Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.