NDST1

Gene

N-deacetylase and N-sulfotransferase 1

HGNCHGNC:7680 EnsemblENSG00000070614 NCBI Gene3340

Locus: gene with protein productLocation: 5q33.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asHSST · NST1

View full nomenclature history (6)

Previous symbolsHSST

Alias symbolsNST1

Previous namesN-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

Alias names[Heparan sulfate]-glucosamine N-sulfotransferase 1, N-Deacetylase-N-sulfotransferase 1, heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Autosomal recessive non-syndromic intellectual disability

Osteoarthritis, Hip

Osteoarthritis, Knee

Graves' Disease

Genetic Diseases, Inborn

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Sulfotransferases, membrane bound

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.