NKX6-1

Gene

NK6 homeobox 1

HGNCHGNC:7839 EnsemblENSG00000163623 NCBI Gene4825

Locus: gene with protein productLocation: 4q21.23

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNKX6A · Nkx6.1

View full nomenclature history (4)

Previous symbolsNKX6A

Alias symbolsNkx6.1

Previous namesNK homeobox (Drosophila), family 6, A, NK6 transcription factor related, locus 1 (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetes Mellitus, Type 2

Amino Acid Metabolism, Inborn Errors

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

NKL subclass homeoboxes and pseudogenes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.