NXPE1

Gene

neurexophilin and PC-esterase domain family member 1

HGNCHGNC:28527 EnsemblENSG00000095110 NCBI Gene120400

Locus: gene with protein productLocation: 11q23.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asFAM55A · MGC34290

View full nomenclature history (4)

Previous symbolsFAM55A

Alias symbolsMGC34290

Previous namesfamily with sequence similarity 55, member A, neurexophilin and PC-esterase domain family, member 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Colitis, Ulcerative

Inflammatory Bowel Diseases

Thrombophilia

Cholangitis, Sclerosing

Crohn's Disease

Psoriasis

Spondylitis, Ankylosing

Actinic keratosis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Neurexophilin and PC-esterase domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-07-06.

Open TargetsGene–disease associations from the Open Targets Platform.