Back to discover

PAWR

Gene

pro-apoptotic WT1 regulator

HGNCHGNC:8614EnsemblENSG00000177425NCBI Gene5074
Locus: gene with protein productLocation: 12q21.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known aspar-4 · PAR4
View full nomenclature history (4)
Alias symbolspar-4, PAR4
Previous namesPRKC, apoptosis, WT1, regulator
Alias namesprostate apoptosis response-4

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases
Peripheral Arterial Disease
Glaucoma
Helicobacter Infections
Coronary Artery Disease
Adverse effect
Alcohol drinking
Acne Vulgaris

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.