POLR2C

Gene

RNA polymerase II subunit C

HGNCHGNC:9189 EnsemblENSG00000102978 NCBI Gene5432

Locus: gene with protein productLocation: 16q21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asRPB3

View full nomenclature history (3)

Alias symbolsRPB3

Previous namespolymerase (RNA) II (DNA directed) polypeptide C (33kD)

Alias namesRNA polymerase II subunit 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

HIV Infections

Dengue

Influenza, Human

Genetic non-acquired premature ovarian failure

Neurodegenerative Diseases

Primary Ovarian Insufficiency

Infertility

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

RNA polymerase subunits

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.