PRDM9

Gene

PR/SET domain 9

HGNCHGNC:13994 EnsemblENSG00000164256 NCBI Gene56979

Locus: gene with protein productLocation: 5p14.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asMSBP3 · PFM6 · ZNF899 · KMT8B · Meisetz

View full nomenclature history (11)

Previous symbolsMSBP3

Alias symbolsPFM6, ZNF899, KMT8B, Meisetz

Previous namesminisatellite binding protein 3, 115kDa, minisatellite binding protein 3 (115kD), PR domain containing 9, PR domain 9

Alias namesPR-domain containing protein 9, histone-lysine N-methyltransferase PRDM9

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic non-acquired premature ovarian failure

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Zinc fingers C2H2-typeHistone lysine methyltransferasesPR/SET domain familyKRAB domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-11-07.

Open TargetsGene–disease associations from the Open Targets Platform.