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PRICKLE2

Gene

prickle planar cell polarity protein 2

HGNCHGNC:20340EnsemblENSG00000163637NCBI Gene166336
Locus: gene with protein productLocation: 3p14.1

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asDKFZp686D143
View full nomenclature history (3)
Alias symbolsDKFZp686D143
Previous namesprickle-like 2 (Drosophila), prickle homolog 2 (Drosophila)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodevelopmental Disorders
Smoking cessation
Placental retention
Glaucoma, Open-Angle

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Prickle planar cell polarity proteinsLIM domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.