PRKD1

Gene

protein kinase D1

HGNCHGNC:9407 EnsemblENSG00000184304 NCBI Gene5587

Locus: gene with protein productLocation: 14q12

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Serine/threonine-protein kinase D1Q15139

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPRKCM · PKD1 · PKCM · PKD · PKC-mu

View full nomenclature history (6)

Previous symbolsPRKCM

Alias symbolsPKD1, PKCM, PKD, PKC-mu

Previous namesprotein kinase C, mu

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Myeloid, Acute

Atrial Fibrillation

Schizophrenia

Neurodegenerative Diseases

Intelligence

Diabetes Mellitus, Type 2

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Pleckstrin homology domain containingProtein kinase D family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2026-04-07.

Open TargetsGene–disease associations from the Open Targets Platform.