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PRTN3

Gene

proteinase 3

HGNCHGNC:9495EnsemblENSG00000196415NCBI Gene5657
Locus: gene with protein productLocation: 19p13.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPR-3 · ACPA · C-ANCA · AGP7 · MBT · P29
View full nomenclature history (9)
Alias symbolsPR-3, ACPA, C-ANCA, AGP7, MBT, P29
Alias namesmyeloblastin, serine proteinase, neutrophil, Wegener granulomatosis autoantigen

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Glomerulonephritis, IGA
Stroke
Arthritis, Rheumatoid
Granulomatosis with polyangiitis
Alcohol drinking
Arthritis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Granule associated serine proteases of immune defenceElastases

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.