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RPS27

Gene

ribosomal protein S27

HGNCHGNC:10416EnsemblENSG00000177954NCBI Gene6232
Locus: gene with protein productLocation: 1q21.3

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Small ribosomal subunit protein eS27P42677

Protein · therapeutic target

Clinically validated target · 1 approved medicine against this target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known aseS27 · MPS-1 · MPS1 · S27
View full nomenclature history (6)
Alias symbolseS27, MPS-1, MPS1, S27
Previous namesribosomal protein S27 (metallopanstimulin 1)
Alias namesmetallopanstimulin 1

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Influenza, Human
Cystic Fibrosis
COVID-19
Severe Acute Respiratory Syndrome
Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

S ribosomal proteins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-03-10.
Open TargetsGene–disease associations from the Open Targets Platform.