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SARM1

Gene

sterile alpha and TIR motif containing 1

HGNCHGNC:17074EnsemblENSG00000004139NCBI Gene23098
Locus: gene with protein productLocation: 17q11.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSARM · SAMD2 · KIAA0524
View full nomenclature history (3)
Alias symbolsSARM, SAMD2, KIAA0524

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Hypertension
Temporal arteritis
Heart Septal Defects, Ventricular
Amyotrophic Lateral Sclerosis
Stroke
Alzheimer's Disease
COVID-19

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Sterile alpha motif domain containingTIR domain containingArmadillo like helical domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.