SEMA4D

Gene

semaphorin 4D

HGNCHGNC:10732 EnsemblENSG00000187764 NCBI Gene10507

Locus: gene with protein productLocation: 9q22.2

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSEMAJ · C9orf164 · CD100 · coll-4 · FLJ39737

View full nomenclature history (8)

Previous symbolsSEMAJ, C9orf164

Alias symbolsCD100, coll-4, FLJ39737

Previous namessema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, chromosome 9 open reading frame 164

Alias namesM-sema G

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Cholangitis, Sclerosing

Squamous Cell Carcinoma of Head and Neck

Arthritis, Rheumatoid

Melanoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesImmunoglobulin like domain containingSemaphorins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.