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SETD1B

Gene

SET domain containing 1B, histone lysine methyltransferase

HGNCHGNC:29187EnsemblENSG00000139718NCBI Gene23067
Locus: gene with protein productLocation: 12q24.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asKIAA1076 · Set1B · KMT2G
View full nomenclature history (4)
Alias symbolsKIAA1076, Set1B, KMT2G
Previous namesSET domain containing 1B

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Genetic Diseases, Inborn
Neurodevelopmental Disorders
Complex neurodevelopmental disorder
Epilepsy
Escherichia coli Infections
Adenocarcinoma of Lung

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Histone lysine methyltransferasesRNA binding motif containingSET domain containing

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2024-11-07.
Open TargetsGene–disease associations from the Open Targets Platform.