SIGLEC1

Gene

sialic acid binding Ig like lectin 1

HGNCHGNC:11127 EnsemblENSG00000088827 NCBI Gene6614

Locus: gene with protein productLocation: 20p13

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

SialoadhesinQ9BZZ2

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSN · SIGLEC-1 · CD169 · FLJ00051 · FLJ00055 · FLJ00073 · FLJ32150 · dJ1009E24.1

View full nomenclature history (10)

Previous symbolsSN

Alias symbolsSIGLEC-1, CD169, FLJ00051, FLJ00055, FLJ00073, FLJ32150, dJ1009E24.1

Previous namessialoadhesin, sialic acid binding Ig-like lectin 1, sialoadhesin

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Neurodegenerative Diseases

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesV-set domain containingC2-set domain containingI-set domain containingSialic acid binding Ig like lectins

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-05-09.

Open TargetsGene–disease associations from the Open Targets Platform.