SIRPG

Gene

signal regulatory protein gamma

HGNCHGNC:15757 EnsemblENSG00000089012 NCBI Gene55423

Locus: gene with protein productLocation: 20p13

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSIRPB2 · bA77C3.1 · SIRP-B2 · SIRPgamma · CD172g

View full nomenclature history (7)

Previous symbolsSIRPB2

Alias symbolsbA77C3.1, SIRP-B2, SIRPgamma, CD172g

Previous namessignal-regulatory protein beta 2, signal-regulatory protein gamma

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetes Mellitus, Type 1

Arthritis, Rheumatoid

Narcolepsy-cataplexy syndrome

Spermatogenic failure

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

CD moleculesV-set domain containingC1-set domain containingSignal regulatory proteinsIg-like cell adhesion molecule family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.