SLC1A2

Gene

solute carrier family 1 member 2

HGNCHGNC:10940 EnsemblENSG00000110436 NCBI Gene6506

Locus: gene with protein productLocation: 11p13

Encodes

via encodes

The protein product this gene encodes, reached through the canonical GENE→PROTEIN (encodes) relation. Its biology, drugs, indications, trials and therapeutic evidence live on the protein's own page.

Excitatory amino acid transporter 2P43004

Protein · therapeutic target

Explore protein biology & therapeutics

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asGLT-1 · GLT1 · EAAT2 · HBGT

View full nomenclature history (8)

Alias symbolsGLT-1, GLT1, EAAT2, HBGT

Previous namessolute carrier family 1 (glial high affinity glutamate transporter), member 2

Alias namesglutamate transporter-1, Excitatory amino acid transporter 2, human brain glutamate transporter

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetes Mellitus, Type 2

Hypothyroidism

Neurodegenerative Diseases

Thyroid Diseases

Undetermined early-onset epileptic encephalopathy

Myxedema

Vitiligo

Stroke

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Solute carrier family 1

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.