Back to discover

SLC9A3

Gene

solute carrier family 9 member A3

HGNCHGNC:11073EnsemblENSG00000066230NCBI Gene6550
Locus: gene with protein productLocation: 5p15.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asNHE3 · NHE-3
View full nomenclature history (6)
Previous symbolsNHE3
Alias symbolsNHE-3
Previous namessolute carrier family 9 (sodium/hydrogen exchanger), isoform 3, solute carrier family 9 (sodium/hydrogen exchanger), member 3, solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Alias namesSodium/hydrogen exchanger 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Hyperphosphatemia
Irritable Bowel Syndrome
Neurodegenerative Diseases
Cystic Fibrosis
Kidney Failure, Chronic
Constipation
Autism Spectrum Disorder
Alcohol drinking

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Solute carrier family 9

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.