SLF2

Gene

SMC5/6 complex localization factor 2

HGNCHGNC:17814 EnsemblENSG00000119906 NCBI Gene55719

Locus: gene with protein productLocation: 10q24.31

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asC10orf6 · FAM178A · FLJ10512 · FLJ25012 · hNSE6

View full nomenclature history (8)

Previous symbolsC10orf6, FAM178A

Alias symbolsFLJ10512, FLJ25012, hNSE6

Previous namesSMC5-SMC6 complex localization factor 2, chromosome 10 open reading frame 6, family with sequence similarity 178, member A

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Anaphylaxis

Genetic Diseases, Inborn

Obesity disorder

Vascular Diseases

Esophageal Squamous Cell Carcinoma

Lymphoma, Large B-Cell, Diffuse

Sleep Apnea Syndromes

Lymphoma

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2025-06-16.

Open TargetsGene–disease associations from the Open Targets Platform.