SMC4

Gene

structural maintenance of chromosomes 4

HGNCHGNC:14013 EnsemblENSG00000113810 NCBI Gene10051

Locus: gene with protein productLocation: 3q25.33

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSMC4L1 · hCAP-C · CAP-C

View full nomenclature history (5)

Previous symbolsSMC4L1

Alias symbolshCAP-C, CAP-C

Previous namesSMC4 (structural maintenance of chromosomes 4, yeast)-like 1, SMC4 structural maintenance of chromosomes 4-like 1 (yeast)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Renal Insufficiency

Diabetes Mellitus, Type 2

Scleroderma, Systemic

Lupus Erythematosus, Systemic

Diabetes Mellitus

Arthritis, Rheumatoid

Myositis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Structural maintenance of chromosomes proteinsCondensin I subunitsCondensin II subunitsMicroRNA protein coding host genes

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.