SRSF8

Gene

serine and arginine rich splicing factor 8

HGNCHGNC:16988 EnsemblENSG00000263465 NCBI Gene10929

Locus: gene with protein productLocation: 11q21

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSFRS2B · SRP46

View full nomenclature history (5)

Previous symbolsSFRS2B

Alias symbolsSRP46

Previous namessplicing factor, arginine/serine-rich 2B, serine/arginine-rich splicing factor 8

Alias namesSR splicing factor 8

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Leukemia, Myeloid, Acute

Lung carcinoma

Lung Neoplasms

Mood Disorders

Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Serine and arginine rich splicing factors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.