TFAP2B

Gene

transcription factor AP-2 beta

HGNCHGNC:11743 EnsemblENSG00000008196 NCBI Gene7021

Locus: gene with protein productLocation: 6p12.3

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asAP2-B · AP-2beta

View full nomenclature history (4)

Alias symbolsAP2-B, AP-2beta

Previous namestranscription factor AP-2 beta (activating enhancer-binding protein 2 beta), transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Diabetes Mellitus, Type 2

Diabetes Mellitus

Glaucoma, Open-Angle

Glaucoma

Genetic Diseases, Inborn

Obesity disorder

Nephrolithiasis

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Transcription factor AP-2 family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.

Open TargetsGene–disease associations from the Open Targets Platform.