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THAP12

Gene

THAP domain containing 12

HGNCHGNC:9440EnsemblENSG00000137492NCBI Gene5612
Locus: gene with protein productLocation: 11q13.5

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asPRKRIR · P52rIPK · DAP4 · THAP0
View full nomenclature history (8)
Previous symbolsPRKRIR
Alias symbolsP52rIPK, DAP4, THAP0
Previous namesprotein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
Alias namesdeath-associated protein 4, P58IPK-regulatory protein, 52 kDa repressor of the inhibitor of the protein kinase

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

MODY
Abortion, Spontaneous
Ovarian neoplasm
Crohn's Disease
Obesity disorder
Transient neonatal diabetes mellitus
Diabetes mellitus, transient neonatal, 3

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

THAP domain family

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.