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TLR5

Gene

toll like receptor 5

HGNCHGNC:11851EnsemblENSG00000187554NCBI Gene7100
Locus: gene with protein productLocation: 1q41

Also known as

Symbols and names change; identity (the HGNC ID) does not. Previous and alternative forms are kept distinct.

Also known asSLEB1 · TIL3 · FLJ10052 · MGC126430 · MGC126431
View full nomenclature history (8)
Previous symbolsSLEB1
Alias symbolsTIL3, FLJ10052, MGC126430, MGC126431
Previous namessystemic lupus erythematosus susceptibility 1, toll-like receptor 5
Alias namesToll/interleukin-1 receptor-like protein 3

Associated diseases

via associated_with

Diseases linked to this gene through the canonical GENE→DISEASE (associated_with) relation, drawn from Open Targets' top-ranked associations by overall score — not the full association set. Disease-level detail lives on each disease's own page.

Immunologic Deficiency Syndromes
Alzheimer's Disease
Drug Hypersensitivity
Dermatitis, Contact
Alcohol drinking
Pre-Eclampsia
Hypotension
Neoplasms

Drawn from Open Targets’ top 10 associations by overall score for this gene — the subset resolved to a canonical disease. Lower-ranked associations, and diseases not yet canonicalised, are not shown.

Gene family

HGNC gene-group membership.

Toll like receptors

Provenance

HGNCCanonical human gene identity from HGNC (release 2026-07-07), updated 2023-01-20.
Open TargetsGene–disease associations from the Open Targets Platform.